Molecular Evolution

Genome Project

Bioinformatics

Astrobiology

Articles

Silva LL, Marcet-Houben M, Zerlotini A, Gabaldón T, Oliveira G, Nahum LA.
Evolutionary histories of expanded peptidase families in Schistosoma mansoni.
Mem Inst Oswaldo Cruz. 2011 Nov;106(7):864-77. PMID: 22124560.

Avelar LG, Nahum LA, Andrade LF, Oliveira G (2011) Functional Diversity of the Schistosoma mansoni Tyrosine Kinases. J Signal Transduct. 603290. PMID: 21776387.

Andrade LF, Nahum LA, Avelar LGA, Silva LL, Zerlotini A, Ruiz JC, Oliveira O (2011) Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni. BMC Genomics 12(1):215. PMID: 21548963.

Oliveira SB, Ibraim IC, Tadei WP, Ruiz JC, Nahum LA, Brito CFA, Moreira LA. (2011) Identification of a fibrinogen-related protein (FBN9) gene in neotropical anopheline mosquitoes. Malaria Journal. 10:21. PMID : 21288344.

Nahum LA, Goswami S, Serres MH. (2009) Protein families reflect the metabolic diversity of organisms and provide support for functional prediction. Physiol Genomics. 38(3):250-60. PMID: 19491149.

Nahum LA, Reynolds MT, Wang ZO, Faith JJ, Jonna R, Jiang ZJ, Meyer TJ, Pollock DD. (2006) EGenBio: a data management system for evolutionary genomics and biodiversity. BMC Bioinformatics. 7 Suppl 2:S7. PMID: 17118150.

Camargo MM, Nahum LA. (2005) Adapting to a changing world: RAG genomics and evolution. Hum Genomics. 2(2):132-7. PMID: 16004728.

Nahum LA, Pereira SL, Fernandes, F.M.C., Matioli, S.R. and Wajntal A (2003) Diversification of Ramphastinae (Aves, Ramphastidae) prior to the Cretaceous/Tertiary boundary as shown by molecular clock of mtDNA sequences. Genetics and Molecular Biology 26(4):411-418.

Serres MH, Gopal S, Nahum LA, Liang P, Gaasterland T, Riley M. (2001) A functional update of the Escherichia coli K-12 genome. Genome Biol. 2(9):RESEARCH0035. PMID: 11574054.

Nahum LA, Riley M. (2001) Divergence of function in sequence-related groups of Escherichia coli proteins. Genome Res. 11(8):1375-81. PMID: 11483578.

Miyaki CY, Griffiths, R., Orr, K., Nahum LA, Pereira SL and Wajntal A (1998) Sex identification of parrots, toucans, and curassows by PCR: perspectives for wild and captive population studies. Zoo Biology 17:415-423.

Book chapters

Nahum LA (2011) Genome Evolution. In: Molecular Biology and Evolution. S.R. Matioli editor. 2nd edition. Holos Editora, Ribeirão Preto, SP – Brazil. [in press]

Nahum LA and Pereira SL (2008) Phylogenomics, Protein Family Evolution, and the Tree of Life: An Integrated Approach between Molecular Evolution and Computational Intelligence. In: Smolinski TG, Milanova MG, Hassanien A-E (eds), Studies in Computational Intelligence (SCI) 122, 259–279. Springer-Verlag Berlin Heidelberg.

Nahum LA (2001) Genome Evolution. In: Molecular Biology and Evolution. S.R. Matioli editor. 1st edition. Holos Editora, Ribeirão Preto, SP – Brazil.

Research Insights

Mitochondrial genomes of plants are much larger than those of mammals and often contain conserved open reading frames (ORFs) of unknown function. Here, we show that one of these conserv...

Miniature tomato, S. lycopersicum cultivar Micro- Tom, was grown as described previously.22 Roots were harvested 5 weeks after germination. Hypocotyl and cotyledon were harvested 3 weeks after germination. Third leaves were harvested 3 weeks after germ....

Initial gene discovery efforts through analysis of genome sequences and identification and characterization of expressed RNAs have revealed that only a relatively small portion of the genome is transcribed into protein coding mRNAs ...

Comparative genetics and genomics use knowledge from different species to define important evolutionary relationships, an important aspect of which is the physical and genetic synteny (two or more homologous loci found on a single chromosome) and ...